Fill-It - automated cell banking, rapid dispensing of cell suspensions from bulk stock
High quality automated cell banking relies on the rapid aseptic preparation of cryovials. Issues exist with standard manual methods as they are prone to variation, place constraints on batch sizes, and repetitive tasks raise operator health concerns.
Fill-It is a standalone product for automated cell banking, dispensing cell suspensions and other liquids into screw-cap microtubes and cryovials, and includes automation for removing and replacing the tube caps.
Fill-It enables the rapid creation of high quality, consistent stock tubes for centralised automated cell line libraries, screening operations or GMP production cell banks and can be used with both mammalian and microbial cell suspensions. The system may also be used for the rapid dispensing of other biological and non-biological liquids into screw top microtubes and cryovials.
A key limitation on the size of a batch of cryovials for automated cell banking is how much cell suspension can be processed before the quality is unduly affected by the toxic effects of cryopreservative. The faster, more efficient processing offered by Fill-It allows cell banks to be created in a shorter period of time. This also leads to the possibility of creating larger cell banks within the safe time limit for cell exposure to cryopreservation buffers. Automated cell banking within a single process rather than multiple smaller runs means that cell bank QC costs are reduced so leading to significant cost savings and a rapid return on investment.
Fill-It - key applications
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