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automated roller bottle processing

Automated roller bottle processing - Cellmate

Automated roller bottle processing and the processes needed to culture cells in fermenters, bioreactors and T-flasks are fully automated using Cellmate. Cellmate takes cell culture processing from the lab bench to high volume production without process change.
The latest generation of Cellmate is supplied with software to support the validation of the system, if used in processes that require compliance with a 21 CFR Part 11.
Cellmate automates:
  • Automated roller bottle processing
  • Cell seeding
  • Cell sheet rinsing
  • Media changing
  • Transient transfection
  • Bottle gassing
  • Enzymatic and non-enzymatic harvesting
  • Harvesting by mechanical scraping
Cellmate offers:
  • Scale up without process change or regulatory re-approval
  • Consistency of product - day to day, batch to batch
  • Operator safety - elimination of repetitive strain injury risk to staff
  • Dramatic reduction in time to market
Originally developed for the demanding GMP environment, over 70 Cellmates have now been installed across the range of cell culture applications in manufacturing and research.
Applications include
  • Automated roller bottle processing
  • Cell culture in fermenters and bioreactors
  • High throughput screening
  • Cell therapies
  • Gene therapies
  • Tissue engineering
  • Therapeutic proteins
  • Human viral vaccines
  • Veterinary viral vaccines
For more information on the Cellmate system:
Learn more about: automated roller bottle processing
Learn more about the full range of Sartorius Stedim TAP Cell Culture Systems