Ambr 15 Cell Culture Generation 2 Ambr 15 Cell Culture

Introducing Ambr® 15 Cell Culture
Generation 2

Ambr® 15 Cell Culture is a high throughput, automated bioreactor system for 24 or 48 parallel cultivations at the 10 - 15 mL microbioreactor scale.

Offering new functionality, a high level of flexibility and improved performance the Generation 2 system is ideally suited for applications including;



Ambr 15 Cell Culture Generation 2 system features
The Ambr® 15 Cell Culture
Generation 2 System Features

The Ambr® 15 Cell Culture workstation controls 24 or 48 disposable bioreactors, offering parallel processing and evaluation of multiple experiments in an automated benchtop system.

  • New Flexible Deck layout
  • New Rapid Vessel Drain functionality
  • New Clone Selection Software Application
  • New Expanded Tip Bin capacity
  • New Liquid Handler capability
  • New Culture Station design

Ambr® 15 is the industry standard microbioreactor system implemented in laboratories world wide. It offers cost effective experimentation by saving on facility space, capital, labour, media and consumables. Integrated metabolite analysis fast tracks implementation of Quality by Design (QbD) principles



The Ambr® 15 Cell Culture
Generation 2 Key Benefits
  • Increased flexibility
  • Improved performance
  • New functionality
  • Enhanced decision making

As biotherapeutics become more complex, and processes more intensified, laboratories around the world are facing bigger challenges developing clones, media and processes.

The Ambr® 15 Cell Culture Generation 2 system addresses these challenges and helps scientists accelerate their research.



Ambr 15 Cell Culture Generation 2 - the benefits
Ambr 15 Cell Culture Generation 2 micro bioreactors

Ambr® 15 Cell Culture microbioreactor vessel

Mimics the characteristics of lab scale bioreactors to enable optimal cell growth, productivity and product quality:

  • 10 - 15 mL microbioreactor working volumes
  • Single-use pH and DO sensors
  • Integrated pitched blade impeller
  • Port for liquid additions and for sampling
  • Available with sparge tube for gassing into impeller mixing zone, or without for headspace gassing
  • Available with temperature compensation for lower temperature applications, experiments below 33°C

The image shows the standard vessel, other variations are available.

To learn more about the unique Ambr® micro bioreactor vessel design, take an interactive tour.



Ambr® Clone Selection - Software for Consistent Screening and Ranking

Ambr® clone selection is a new standalone software application for use with data from Ambr systems to simplify the workflow for cell line screening and ranking.

It can be used in:

  • Cell strain selection
  • Media and feed screening applications

Users define the selection criteria such as cell density, product titer and key product quality attributes and assign priority weightings in order to screen and rank clones. The application uses a unique multivariable desirability assessment feature for clone ranking.



Ambr Clone Selection software



Ambr 15 Cell Culture micro bioreactors

The Ambr® analysis module

The Ambr® analysis module enables automated pH measurement, both for initial microbioreactor pH sensor calibration and subsequent in-process checks; improving pH control and culture performance.

Ambr® 15 is compatible with many other analyzers.



Get more detail on the systems' key applications: cell line selection & development


Request further information on Ambr® 15 Cell Culture
Generation 2

To discuss your requirements please contact us


Request technical notes and bibliography

Request the lastest technical notes and bibliography request info


Video gallery

Video gallery

View video of the key Ambr® 15 Cell Culture Generation 2 workstation processes.



Micro bioreactor tour

Workstation tour

Take an interactive tour of the Ambr® 15 Cell Culture Generation 2 workstation.



Microbioreactor Tour

Micro bioreactor tour

Take an interactive tour of the Ambr® 15 Cell Culture Generation 2 micro bioreactor.



Featured webinar

On-demand webinars

Request access to the full list of webinars, in partnership with Catalent Biologics, WuXi Biologics and Glycotope.




Featured webinar

"High-throughput media & feed screening for cell culture process optimization with multi-parallel micro bioreactors" by Dr Marta Ruiz Guillén, 3P Biopharmaceuticals