ambr 15 fermentation ambr 15 fermentation

ambr® 15 fermentation

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A new microbioreactor system for mircobial strain screening

ambr® 15 fermentation is a new automated microscale bioreactor system designed for microbial screening applications.

Based on the gold-standard ambr 15 technology, it provides a consistent microscale model for early stage microbial strain screening with enhanced capabilities supporting fed-batch microbial cultures.

 

ambr 15f single-use bioreactors
ambr 15 fermentation features:
  • Online monitoring and closed-loop control of pH (6-8) and DO, with independent control of O2 , CO2 and air for each vessel
  • Cascade DO control system for gas flow, stirrer speed and gas mixture
  • Full control of impeller speed, gas flow rates and bioreactor temperature
  • Automated liquid handling for reactor set-up, feeds, base addition and sampling
  • Software controls and monitors all experiments and records data and events with a full audit trail
  • Easy installation into laminar flow hood allowing aseptic operation

 

 

Integrated Online Biomass Measurement

ambr® 15 fermentation is now available with online biomass, a further step forward in advanced microbial process monitoring and control:

  • Real-time continuous growth monitoring for microbial applications
  • Fully automated and non-invasive analysis; does not interrupt experiment or reduce culture levels
  • Effective bubble discrimination in high aeration and agitation environments
  • Reduces the burden of frequent offline manual sampling; freeing up valuable operator time
  • Feedback control of process events possible based on real-time biomass data

 

 

ambr 15f online biomass measurement

 

ambr 15f vessels

 

ambr 15 fermentation vessels

Single-use vessels mimic the characteristics of a classical lab scale bioreactor.

  • Online monitoring and closed-loop control of pH (6-8) and DO, with independent control of O2 , CO2 and air for each vessel
  • Cascade DO control system for gas flow, stirrer speed and gas mixture
  • Full control of impeller speed, gas flow rates and bioreactor temperature
  • Automated liquid handling for reactor set-up, feeds, base addition and sampling
  • Software controls and monitors all experiments and records data and events with a full audit trail
  • Easy installation into laminar flow hood allowing aseptic operation

 

 

ambr 15 fermentation enables:
  • Increased lab productivity by automating experiment setup, sampling and reagent addition for up to 24 experiments in parallel
  • Enhanced capability over shaken cultures with full control of DO and pH in fed-batch culture, impeller stirring, gas sparging and pumped additions of pH reagent and feed
  • Data-rich culture profiles with automated sampling and enough culture volume for many samples during a run
Applications include:

ambr 15 fermentation can be used as a microscale model to enable research in a range of development applications such as:

  • Strain selection
  • Vector screening

 

Request further information on ambr 15 fermentation

To discuss your requirements please contact us

 

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"A novel automated micro bioreactor for high density fed batch microbial screening applications" request poster

 

Explore ambr 15 fermentation in detail
Video gallery

Video gallery

View video of the key ambr 15 fermentation workstation processes.

Micro bioreactor tour

Micro bioreactor tour

Take an interactive tour of the unique ambr 15 fermentation micro bioreactor.

Workstation tour

Workstation tour

View the key features and functionality of the ambr 15 fermentation workstation.

Webinar

Featured webinar

Live webinar April 10th 2019:
"Online Biomass Monitoring in ambr 15 fermentation”